Can Diabetes Be Cured?

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Can Diabetes Be Cured?
Recently, the question was asked: “Can diabetes be totally cured? Can there be any medicine which will cure diabetes totally? ”

My reply:

You might have asked exactly the same questions that everybody else considers, which everyone hopes may have an answer soon. Unfortunately, the idea of “cure” doesn’t appear to affect diabetes.

That’s because diabetes isn’t just one disease, but a collection of different disorders, many of which are autoimmune, the majority of that are genetic, as well as which involve either the destruction from the pancreas’ capability to make insulin, or even the body’s capability to use insulin appropriately (or both). Types of the various kinds of diabetes that will need different methods to be cured: type 1 (autoimmune) diabetes, type 2 (insulin-resistant) diabetes, MODY diabetes (which is really a name covering a minimum of a dozen different monogenetic types of diabetes), post-surgical diabetes (after pancreatectomy surgery), bronze diabetes (medically called hemochromatosis), chemically-induced diabetes (like the diabetes induced by Agent Orange) and Cystic Fibrosis-Related Diabetes. Therefore, any cure that eventually may be developed would possibly only affect a percentage of individuals that have among the many forms of diabetes, and wouldn’t be very likely to cure some of the other kinds of diabetes.

Since diabetes has different causes, it’s also no real surprise that there’s no single medication that will control, let alone cure, all of the different types of diabetes. Some of the forms can be readily treated without the hassle of injections and the risk of weight and hypoglycemia gain that come with insulin therapy, even though giving insulin by injection is probably the closest to a magic bullet to treat the hyperglycemia of all the forms of diabetes.

Would be pancreas transplantation - or better still, transplantation of the islet cells of the pancreas, although the closest to the idea of a medication to cure diabetes, from my way of thinking, isn’t a medication per se. At the price of the patient instead needing to take toxic anti-rejection drugs to decrease the odds that the body will reject the transplant, although such transplants have been tried for many years in patients with type 1 diabetes, and occasionally results in the patients remaining off insulin supplementation for long periods of time. There is a rare form of diabetes that can be prevented by transplantation, by the way: in patients that are undergoing surgery to get rid of the pancreas for any condition called chronic pancreatitis, it’s easy to autotransplant their islets from your pancreas that’s being removed and implant them in to the patient, thus preventing diabetes from developing.